Seems my promotion at work comes with required attendance at meetings. I've so far resisted the urge to request to leave so that I can get something more important done.
Broadly speaking
Nob
Dick
Twat
Wanker
Motherfucker (for US/Canada based TBers)
Cunt
So to go in with “Cunt” in response to “Twat” is fairly significant escalation
Serious point. When I lived in Boston, I got into a serious debate with a very hot chick as to whether Cunt or Motherfucker was worse. I’m really of the opinion that the word for someone who has sex with their mother should be deemed worse than the word for a vagina. She did not agree.
This is often a discussion I have with my work colleagues (out of the work environment, most recently on this past European trip) they take great glee in calling each other cunts, but won’t do it in the US.