No.
Nope.
Affirmative.
People are used to using spreadsheets. Spreadsheets work. If you always use a spreadsheet, you will only know how to do things with spreadsheets.
If I want to quickly analyse a set of data, I'm going to use a spreadsheet. If I need to collect and manage large sets of data collaboratively, and periodically analyse elements of it I'm going to use a database (maybe using a spreadsheet an analysis tool). Spreadsheets can do all of this, so it's easier to use one (and only one personal skill set), but with large sets of data, that needs sharing and versioning, you will run into problems with spreadsheets (even if it's only the logistics of managing independent edits of 'current' versions).
If you want to see what modern database tools, designed to replace the use of spreadsheets (where they are sub-optimal), you can do worse than look at grist, and specifically grist-electron as a stand alone application.