Don't think it even shows that. (He rarely can do that anyway because he's normally used all his subs before stoppage time.)
Why do managers make changes? Injuries, a bit of horses for courses and "we played shit, let's try some new players". We've not had many injuries and not many games where we've played shit. So we just haven't needed to use more players.
Who has played most minutes in the league for us? Sels, Aina, Milenkovic, Murillo. Three of them got the night off completely on Tuesday and the 4th is the goalkeeper (who they wouldn't have expected to play any part). Almost as if they know who to rest.